This website requires JavaScript.

IGUANe: a 3D generalizable CycleGAN for multicenter harmonization of brain MR images

Vincent RocaGr\'egory KuchcinskiJean-Pierre PruvoDorian ManouvriezRenaud Lopes
Feb 2024
0被引用
0笔记
摘要原文
In MRI studies, the aggregation of imaging data from multiple acquisition sites enhances sample size but may introduce site-related variabilities that hinder consistency in subsequent analyses. Deep learning methods for image translation have emerged as a solution for harmonizing MR images across sites. In this study, we introduce IGUANe (Image Generation with Unified Adversarial Networks), an original 3D model that leverages the strengths of domain translation and straightforward application of style transfer methods for multicenter brain MR image harmonization. IGUANe extends CycleGAN architecture by integrating an arbitrary number of domains for training through a many-to-one strategy. During inference, the model can be applied to any image, even from an unknown acquisition site, making it a universal generator for harmonization. Trained on a dataset comprising T1-weighted images from 11 different scanners, IGUANe was evaluated on data from unseen sites. The assessments included the transformation of MR images with traveling subjects, the preservation of pairwise distances between MR images within domains, the evolution of volumetric patterns related to age and Alzheimer$^\prime$s disease (AD), and the performance in age regression and patient classification tasks. Comparisons with other harmonization and normalization methods suggest that IGUANe better preserves individual information in MR images and is more suitable for maintaining and reinforcing variabilities related to age and AD. Future studies may further assess IGUANe in other multicenter contexts, either using the same model or retraining it for applications to different image modalities.
展开全部
机器翻译
AI理解论文&经典十问
图表提取
参考文献
发布时间 · 被引用数 · 默认排序
被引用
发布时间 · 被引用数 · 默认排序
社区问答