Simon WaidAndreas GsponerClaus Schmitzer
...+6
Thomas Bergauer
Nov 2023
0被引用
0笔记
摘要原文
FLASH radiotherapy using proton beams is currently commonly performed in transmission mode. This mitigates the main advantage of proton radiotherapy: large energy deposition in the Bragg peak located in the tumor and low energy deposition in the entrance channel. One challenge on the path to treating using the Bragg peak and pencil-beam scanning are the extremely high dose-rates required for FLASH combined with the required accurate dose-control. We propose the use of pulsed RFKO extraction as a way to control the dose delivered per Voxel. In a first feasibility test dose-rates in pulses of up to 600 Gy were observed, while the granularity at which the dose was delivered is expected to be well below 0.5 Gy.
