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A portable widefield fundus camera with high dynamic range imaging capability

Alfa RossiMojtaba RahimiDavid Le ...+3 Xincheng Yao
Dec 2022
摘要
Fundus photography is indispensable for clinical detection and management ofeye diseases. Limited image contrast and field of view (FOV) are commonlimitations of conventional fundus cameras, making it difficult to detectsubtle abnormalities at the early stages of eye diseases. Further improvementsof image contrast and FOV coverage are important to improve early diseasedetection and reliable treatment assessment. We report here a portable funduscamera, with a wide FOV and high dynamic range (HDR) imaging capabilities.Miniaturized indirect ophthalmoscopy illumination was employed to achieve theportable design for nonmydriatic, widefield fundus photography. Orthogonalpolarization control was used to eliminate illumination reflectance artifact.With independent power controls, three fundus images were sequentially acquiredand fused to achieve HDR function for local image contrast enhancement. A101{\deg} eye-angle (67{\deg} visual-angle) snapshot FOV was achieved fornonmydriatic fundus photography. The effective FOV can be readily expanded upto 190{\deg} eye-angle (134{\deg} visual-angle) with the aid of a fixationtarget, without the need of pharmacologic pupillary dilation. The effectivenessof HDR imaging was validated with both normal healthy and pathologic eyes,compared to a conventional fundus camera.
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